Cir¹

Your blood vessels form part of your circulatory system, and play the critical role of allowing blood to be transported around the body. The vessels can be likened to a network of tubes around the body with an internal lining called the endothelium.

The endothelium is the largest organ in the body, forming an interface between the bloodstream and the basement membrane. The endothelium consists of endothelial cells, and a matrix of structures that project into the lumen (vessel cavity), known as the 'endothelial glycocalyx'.

The glycocalyx projects into the lumen like a layer of fine hair, and is made up of membrane-bound proteoglycans and glycoproteins.

This layer has been named an 'invisible shield' or 'non-stick lining' by some scientists, as it prevents platelets and leukocytes from sticking to walls. It also plays an important role in controlling vessel permeability, calcification levels and in the regulation of nitric oxide, which acts as a powerful vasodilator and causes blood vessels to expand to allow blood flow.

The ability of blood vessels to transport blood and its constituents is important to your wellbeing, so it can be useful to support blood vessel health as you age. The endothelial glycocalyx is a promising target for supporting healthy blood vessels and circulation.

The Cir¹ formulation provides a unique and synergistic combination of rhamnan sulphate, curcuminoids and a selection of other ingredients to support the maintenance and repair of your blood vessel lining for overall blood vessel health.

→ Supports the maintenance and regeneration of the blood vessel lining (glycocalyx)
→ Supports normal calcification levels and blood vessel flexibility
→ Supports healthy nitric oxide levels, for a normal vasodilatory response and healthy blood pressure
→ Supports a healthy response to factors that damage blood vessels