Research

Egg yolk antibodies (IgY) and their applications in human and veterinary health: A review

DOI: 10.1016/j.intimp.2019.05.015 Summary: This article aims to review IgY's applications in both human and veterinary health.. Research paper authors: E P V Pereira, M F van Tilburg, E O P...

Protective effect of hyperimmune egg yolk IgY antibodies against Eimeria tenella and Eimeria maxima infections

DOI: 10.1016/j.vetpar.2009.04.020 Summary: In this randomized controlled trial, young chicks from hatch were continuously fed a comercially available powder which contained a fraction of purified IgY which was immunized with...

Roles of Zinc Signalling in the Immune System

DOI: 10.1155/2016/6762343 Summary: This review highlights the emerging functional roles of Zn and Zn transporters in immunity, focusing on how crosstalk between Zn and immune-related signaling guides the normal development...

α-Lipoic acid prevents senescence, cell cycle arrest, and inflammatory cues in fibroblasts by inhibiting oxidative stress

DOI: 10.1016/j.phrs.2019.01.003 Summary: In this study, anti-aging potential of α-lipoic acid (α-LA), in rat embryonic fibroblast (REF) cells was assessed. The results of this study show that α-LA has beneficial...

Lipoic acid and autophagy: new insights into stem cell aging

DOI: 10.15252/embr.202051175 Summary: In this issue of EMBO Reports, Du et al report that alpha-lipoic acid (ALA) sustains an active endocytosis-autophagy network that effectively reverses age-dependent ISC hyperplasia in Drosophila...

EGCG protects vascular endothelial cells from oxidative stress-induced damage by targeting the autophagy-dependent PI3K-AKT-mTOR pathway

DOI: 10.21037/atm.2020.01.92 Summary: Our study aimed to investigate the protective effect of EGCG in an endothelial injury model induced by hydrogen peroxide (H2O2) and reveal the possible mechanisms. The results...

Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model

DOI: 10.3390/ijms17081293 Summary: The goal of this study was to investigate whether oleuropein (OLE), the major phenolic compound in olive derivatives, may prevent neuronal degeneration in a cellular dopaminergic model...

Oleuropein Induces AMPK-Dependent Autophagy in NAFLD Mice, Regardless of the Gender2018

DOI: 10.3390/ijms19123948 Summary: The aim of our study was to establish whether the positive Ole-related effects on liver steatosis could be associated with autophagy. Female and male C57BL/6J mice were...

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM

DOI: 10.3892/mmr.2020.11572 Summary: This study aimed to investigate the effects of apigenin on cell proliferation and apoptosis of human melanoma cells A375P and A375SM. Therefore, melanoma cells were treated with...